Peter J Havel Selected Research

Fructose

8/2020	Effects of Dietary Glucose and Fructose on Copper, Iron, and Zinc Metabolism Parameters in Humans.
1/2020	Role of angiopoietin-like protein 3 in sugar-induced dyslipidemia in rhesus macaques: suppression by fish oil or RNAi.
1/2019	Low plasma adropin concentrations increase risks of weight gain and metabolic dysregulation in response to a high-sugar diet in male nonhuman primates.
1/2019	Fructose-induced hypertriglyceridemia in rhesus macaques is attenuated with fish oil or ApoC3 RNA interference.
10/2015	Differential Responses of Plasma Adropin Concentrations To Dietary Glucose or Fructose Consumption In Humans.
3/2015	Chronic oxytocin administration inhibits food intake, increases energy expenditure, and produces weight loss in fructose-fed obese rhesus monkeys.
5/2014	Clinical research strategies for fructose metabolism.
1/2014	Fish oil supplementation ameliorates fructose-induced hypertriglyceridemia and insulin resistance in adult male rhesus macaques.
12/2013	Effects of sugar-sweetened beverages on plasma acylation stimulating protein, leptin and adiponectin: relationships with metabolic outcomes.
7/2012	Consumption of fructose- but not glucose-sweetened beverages for 10 weeks increases circulating concentrations of uric acid, retinol binding protein-4, and gamma-glutamyl transferase activity in overweight/obese humans.

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Peter J Havel Research Topics

Disease

55	Insulin Resistance 04/2022 - 02/2002
33	Type 2 Diabetes Mellitus (MODY) 01/2022 - 08/2003
32	Obesity 11/2021 - 02/2002
27	Body Weight (Weight, Body) 10/2021 - 11/2002
16	Weight Loss (Weight Reduction) 01/2021 - 04/2003
14	Weight Gain 10/2021 - 02/2002
14	Overweight 02/2021 - 01/2004
13	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/2020 - 01/2007
12	Cardiovascular Diseases (Cardiovascular Disease) 08/2020 - 01/2004
10	Inflammation (Inflammations) 05/2022 - 06/2008
10	Dyslipidemias (Dyslipidemia) 03/2020 - 02/2008
9	Hyperglycemia 11/2021 - 02/2006
6	Hypertriglyceridemia 01/2020 - 02/2008
5	Diabetes Mellitus 05/2022 - 11/2006
5	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2020 - 01/2002
5	Hyperinsulinism (Hyperinsulinemia) 02/2012 - 09/2002
4	Metabolic Diseases (Metabolic Disease) 10/2019 - 10/2012
4	Abdominal Obesity 01/2016 - 08/2011
4	Hyperlipidemias (Hyperlipidemia) 07/2011 - 02/2002
3	Hypoglycemia (Reactive Hypoglycemia) 12/2020 - 01/2002
3	Atherosclerosis 12/2017 - 06/2008
3	Glucose Intolerance 05/2010 - 06/2002
2	Non-alcoholic Fatty Liver Disease 02/2022 - 12/2010
2	Prediabetic State (Prediabetes) 01/2022 - 02/2012
2	Hypercholesterolemia 01/2018 - 09/2016
2	Fibrosis (Cirrhosis) 12/2017 - 12/2010
2	Fatty Liver 12/2017 - 07/2012
2	Coronary Artery Disease (Coronary Atherosclerosis) 02/2017 - 06/2007
2	Proteinuria 01/2017 - 01/2017
2	Adenocarcinoma 01/2016 - 12/2015
2	Gastroesophageal Reflux (GERD) 01/2016 - 12/2015
2	Barrett Esophagus (Barrett's Esophagus) 01/2016 - 12/2015
2	Nausea 06/2015 - 03/2015
2	Myocardial Infarction 08/2013 - 12/2006
2	Coronary Disease (Coronary Heart Disease) 01/2009 - 12/2006
1	Alcoholic Fatty Liver 02/2022
1	Dysbiosis 11/2021

Drug/Important Bio-Agent (IBA)

46	Glucose (Dextrose)FDA LinkGeneric 04/2022 - 06/2002
39	Insulin (Novolin)FDA Link 04/2022 - 01/2002
28	FructoseIBA 08/2020 - 02/2002
26	AdiponectinIBA 01/2019 - 02/2002
23	LipidsIBA 04/2022 - 04/2003
23	LeptinIBA 10/2021 - 02/2002
20	Triglycerides (Triacylglycerol)IBA 01/2021 - 02/2002
12	SugarsIBA 02/2021 - 02/2004
10	Hormones (Hormone)IBA 01/2020 - 02/2002
7	Oxytocin (Pitocin)FDA LinkGeneric 10/2021 - 03/2015
7	Lipoproteins (Lipoprotein)IBA 10/2021 - 01/2009
6	GhrelinIBA 01/2016 - 04/2003
5	Glucagon (Glukagon)FDA Link 11/2021 - 01/2002
4	High Fructose Corn SyrupIBA 04/2022 - 06/2013
4	Sucrose (Saccharose)IBA 10/2021 - 06/2013
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 05/2008
4	Fish OilsIBA 01/2020 - 12/2010
4	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 12/2016 - 04/2014
4	Biological ProductsIBA 01/2016 - 02/2002
4	Hydrocortisone (Cortisol)FDA LinkGeneric 06/2015 - 11/2004
3	Glucagon-Like Peptide 1 (GLP 1)IBA 11/2021 - 10/2010
3	Uric Acid (Urate)IBA 10/2021 - 07/2012
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2002
3	Dietary SugarsIBA 01/2020 - 05/2009
3	Fatty Acids (Saturated Fatty Acids)IBA 12/2017 - 02/2002
3	des-Arg-(77)- complement C3aIBA 12/2013 - 02/2002
3	salicylhydroxamic acid (SHAM)IBA 12/2013 - 06/2010
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 02/2022 - 02/2008
2	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2022 - 01/2021
2	Nonesterified Fatty Acids (NEFA)IBA 01/2021 - 02/2008
2	C-PeptideIBA 12/2020 - 01/2014
2	Aspartame (NutraSweet)IBA 08/2020 - 01/2018
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 03/2006
2	NitrogenIBA 01/2017 - 01/2017
2	Protein Tyrosine PhosphatasesIBA 01/2017 - 04/2009
2	Urea (Carbamide)FDA LinkGeneric 01/2017 - 01/2017
2	CarbohydratesIBA 01/2016 - 11/2008
2	Insulin ReceptorIBA 09/2014 - 06/2002
2	Liraglutide FDA Link 09/2014 - 10/2010
2	Bile Acids and Salts (Bile Acids)IBA 03/2013 - 08/2012
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2013 - 09/2002
2	Blood Glucose (Blood Sugar)IBA 10/2012 - 11/2007
2	EnzymesIBA 01/2012 - 08/2011
2	Leptin ReceptorsIBA 12/2010 - 10/2009
2	Tyrosine (L-Tyrosine)FDA Link 04/2009 - 06/2002
2	ApolipoproteinsIBA 11/2008 - 04/2003
1	Transcription Factors (Transcription Factor)IBA 05/2022
1	Oxidants (Oxidizing Agents)IBA 05/2022
1	AntioxidantsIBA 05/2022
1	OxylipinsIBA 02/2022
1	Lys(8)- oxytocin (OXL)IBA 02/2022
1	EndocannabinoidsIBA 02/2022
1	Estrogens (Estrogen)FDA Link 01/2022
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2022
1	Oxidoreductases (Dehydrogenase)IBA 11/2021
1	Pancreatic HormonesIBA 11/2021
1	Pyruvic Acid (Pyruvate)IBA 11/2021
1	CatecholaminesIBA 10/2021
1	Choline (Choline Chloride)IBA 01/2021

Therapy/Procedure

5	Bariatric Surgery 01/2018 - 06/2008
4	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2018 - 04/2003
3	Therapeutics 11/2021 - 11/2006
2	Glycemic Control 11/2021 - 02/2006